The objectives of intraoperative biopsy are:

① To determine the nature of the lesion in order to determine the surgical plan. For example, for a lesion of unknown nature, take the lesion on the operating table for examination and wait 20-30 minutes. If the frozen section is diagnosed as inflammatory or benign tumor, the surgical scope is very small. If it is malignant, radical mastectomy with enlarged excision is performed immediately.

② Understand the lesion, especially the growth and diffusion of malignant tumor, such as the scope and depth of invasion, whether there is lymph node metastasis, and whether the surgical resection of the marginal tissue is tumor cells, etc., to determine the scope of surgery.

③ Determine whether the specimen contains predetermined tissues, organs or lesions. If the parathyroid gland is to be removed, but it is not clear in the operation field, cryobiopsy can help confirm.

The greatest advantage of intraoperative biopsy is that during the operation, it can be confirmed for the lesion of unknown nature, so that the clinical can immediately determine the surgical treatment plan, avoid the second time for therapeutic surgery. The patient can avoid a second operation and the medical staff can save the fatigue of another operation. Secondly, it plays a magnifying glass role for surgeons to install a hundred times, can know how deep the lesion invasion, how far, there are no tumor cells at the cutting edge, etc..

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