What is a pathological biopsy

Pathological biopsy, or "biopsy" for short, is an important method for disease diagnosis by taking a living tissue for morphological examination. Biopsy is mainly used for the differentiation of tumor and non-tumor diseases, benign and malignant tumors, to judge the extent and scope of malignant tumor growth, invasion and metastasis, and to observe the degree of disease development or treatment response. According to the different instruments and methods used in biopsy, there are incisional biopsy, which is to cut part of the lesion and its adjacent normal tissue; Excision biopsy is the removal of all lesions for examination; Endoscopic biopsy, in which a small amount of diseased tissue is taken by endoscopic forceps; Needle aspiration biopsy is a small amount of tissue sucked up with a puncture needle. In addition, there are scraping, drilling and other ways. The biopsy tissue was then selected for paraffin sections and histologically examined under a microscope, if necessary by electron microscopy or immunohistochemistry. In addition, there is a rapid biopsy, also known as a frozen biopsy, which is often used to make timely judgments during surgery to help determine the scope or method of surgery.