How many milliliters of bone marrow can be donated at one time? Will 200-300 affect the body? Please tell me in detail, thank you

Originally, the bone marrow was taken from the iliac bone with a syringe-like puncture needle, and the amount was very small. Now, hematopoietic stem cells are simply separated from the peripheral blood.

Specific steps:

1. The patient searches in the database of Chinese hematopoietic stem cell donors. After the initial matching is successful, you will be notified to perform a physical examination and perform high-resolution. If the high-resolution results match, then enter the following link, if they don’t match, you can’t donate.

2. After the high-resolution match, according to the patient's schedule, enter the hospital five days before the collection day, and have a simple physical examination. Within four days, intravenous injection of mobilizer every day (for the description of mobilizer, please see the post on hematopoietic stem cell basic knowledge) .

That is, admission on day 0, injection of mobilizer on day 1 to 4, and collection on day 5.

3. Collection method and process: Modern hematopoietic stem cell transplantation uses hematopoietic stem cells collected from peripheral blood. Scientifically mobilize the hematopoietic stem cells in the bone marrow blood into the peripheral blood, collect whole blood from the vein of the donor's arm, extract the hematopoietic stem cells through a blood cell separator, and inject other blood components back into the donor's body. Since the entire collection process is carried out in a closed and medically safe environment, it is extremely safe. After the collection is completed, some slight pain and discomfort will soon disappear. So far, there is no report of harm to donors caused by the collection of peripheral blood stem cells. Please believe that we "will not kill another in order to save one."

Collect a total of approximately 10 grams of hematopoietic stem cells. Contains part of the blood components, generally 50-100 ml. The blood volume is less than a donation of whole blood. Moreover, the human body has a strong ability to regenerate hematopoietic stem cells. Under normal circumstances, various cells of the human body are constantly metabolizing every day, undergoing a cycle of aging and death. After blood loss or donation of hematopoietic stem cells, the bone marrow can be stimulated to accelerate hematopoiesis. Within 1-2 weeks, various blood cells in the blood will return to their original levels. Therefore, donating hematopoietic stem cells will not affect health.

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