Does needle bone marrow transplantation affect the health of the donor?

The second question that donors worry about is "side effects of bone marrow donation". Since the donation of peripheral blood hematopoietic stem cells is similar to unpaid blood donation, the question becomes: Will the mobilization needle have adverse effects on the human body?

The answer is yes.

The main component of the mobilization needle is recombinant human granulocyte colony-stimulating factor (rhG-CSF). It has a long name, but don't worry, the body already has some human granulocyte colony-stimulating factor (hG-csf), which is important for maintaining normal blood function.

The worst effects of granulocyte colony-stimulating factor are seen in vitro. Studies have FOUND receptors FOR GRANULOCyte COLONy-stimulating FACTOR ON THE SURFACE OF LEUKEMIC CELLS, WHICH MAY SUGGEST A LINK.

Fortunately, neither in vivo nor in long-term follow-up has found evidence of CFR causing tumors.

The short-term adverse effects of the mobilization needle, including low fever, fatigue, muscle soreness, etc., generally do not require special treatment and will resolve spontaneously after stopping the drug.

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