Endoscopic Ultrasound-guided Fine Needle

Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) remains the most common EUS-guided tissue acquisition technique. This study aimed to evaluate the performance of a new Franseen tip fine needle biopsy (FNB) device for EUSguided sampling of solid lesions and compare it with the historical FNA technique.

There is a high degree of variability with the diagnostic yield of FNA needles , especially for pancreatic lesions. The diagnostic accuracy ranges from 78% to 95%. The diagnostic yield is even lower when it is used for mediastinal masses and gastrointestinal stromal tumors. A retrospective study on 37 patients reported a sensitivity of 78.4% for the FNA needle. FNA needles do not provide core tissue for immunohistochemical staining and for histology. EUS‑FNB needle was developed over a decade ago to overcome this limitation. Different principles have been used to design different types of FNB needles.

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