Why is a bone marrow biopsy required for the diagnosis of leukemia?

There are more than a dozen types of leukemia that are definitively diagnosed, and the prognosis varies widely, as do treatments. Peripheral venous blood examination alone cannot accurately classify, and bone biopsy is the best method. Bone puncture is also essential for the diagnosis of diseases such as multiple myeloma. For unexplained bone metastases, bone puncture may obtain tumor cells to make a clear diagnosis.

Disease staging Malignant lymphoma often invades the bone marrow, and even complicated with leukemia, indicating that the tumor has entered an advanced stage. In order to accurately determine its clinical stage and treatment plan, bone biopsy should be routinely performed before the first treatment.

Judgment of curative effect During the treatment of leukemia, multiple myeloma and malignant lymphoma, multiple site and multiple bone puncture examinations are required. By dynamically observing the bone marrow status, the curative effect can be judged and the treatment plan adjusted in time.

Ensuring the safety of treatment In the process of tumor radiotherapy and chemotherapy, bone puncture can help doctors understand the patient's bone marrow function. During chemotherapy, the drug should be administered as appropriate according to the degree of myeloproliferation, so as to grasp the best timing and ensure the safety of medication. During radiotherapy, if the patient's white blood cells and other indicators continue to be low, the dose should be adjusted according to the state of the bone marrow.

Bone piercing is very convenient and safe.

Many patients think that bone piercing is a very scary thing, but it is not. The method of bone piercing is very simple. Generally, a small amount of anesthesia is injected locally at the anterior (or posterior) upper ridge of the ilium or the sternum, and a small drop of bone marrow tissue is extracted with a bone piercing needle. A skilled doctor operates the entire process of bone piercing, but only a few minutes. After the bone marrow is extracted, the patient can get up and move immediately.

Some patients feel that bone piercing will damage "vigor", which is also a misunderstanding. The average bone marrow hematopoietic tissue of a normal person is 2600 grams, and the amount of bone marrow puncture is only 0.2-0.3 grams. In addition, the bone marrow is a tissue with strong regeneration ability of the human body. , and will not cause long-term damage.

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