Why is a bone marrow biopsy required for severe anemia?

The cytological examination of the bone marrow smear can be used to understand the formation of various cells in the bone marrow, the changes in the morphology and composition of various cells, and the discovery of abnormal cells, so as to confirm the diagnosis, observe the curative effect, and estimate the prognosis. Bone marrow is the main organ of hematopoiesis. The root of many blood diseases originates from the bone marrow. After suffering from blood diseases, the hematopoietic cells in the bone marrow often change. Therefore, a small amount of bone marrow is extracted to analyze the hematopoietic cells in it. Affirmative diagnosis or support for clinical diagnosis. The diseases that can make a positive diagnosis include: various types of leukemia, multiple myelopathy, Gaucher disease, Niemann-Pick disease, metastatic cancer, some primary infectious diseases, etc. Proposed diseases that meet the diagnosis: such as iron deficiency anemia, aplastic anemia, thrombocytopenic purpura, etc. Such as bone marrow examination found some changes, but the clinical diagnosis can not provide support or negative opinion, can be a reference for further examination. During the treatment of blood diseases, bone marrow examination is often used to analyze the curative effect.

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