Why does the diagnosis of osteosarcoma require biopsy and pathological examination?

Histopathological examination of puncture or incision biopsy is the basis for the diagnosis of osteosarcoma. Needle biopsy histological diagnosis is currently a more clinically developed method. It has the advantage of simple operation. If it can be diagnosed, it can save patients from the pain of a surgical biopsy and reduce medical expenses. The trocar biopsy does not need to cut the skin, the biopsy channel is small, the trauma is small, and the pollution to the surrounding normal tissues is less than that of the open biopsy, which creates good conditions for limb salvage. The accuracy rate of identifying benign and malignant tumors is as high as 95%, and it is the best biopsy method for patients with osteosarcoma. The disadvantage is that a special puncture needle is required, and the tissue mass obtained from puncture is small, which is qualitatively qualitative but difficult to classify. Due to the obvious atypia of bone tumors, there is a certain false negative rate. Clinically, it is generally believed that a positive puncture histopathological pathology can be used as a diagnostic basis; if it is negative, the possibility of malignant disease cannot be completely ruled out. If the clinical symptoms and imaging still cannot rule out the possibility of malignancy, an open biopsy should be considered. Department of Bone and Soft Tissue Oncology, Liaoning Cancer Hospital (Tumor Hospital of China Medical University) Shang Guanning

Histopathological examination of incision biopsy is the most reliable pathological diagnosis method. The open biopsy can see the tumor under direct vision, and the material is accurate, which meets the requirements of pathological examination, and the diagnosis accuracy rate is 98%. Therefore, open biopsy can be used in cases where needle biopsy is difficult or difficult to diagnose. The cut tissue block must be large enough. Hospitals with conditions should perform frozen pathological examination during the biopsy. After the frozen pathology confirms that the cut tissue is indeed tumor tissue rather than necrotic tissue, the incision should be sutured to avoid the occurrence of a biopsy operation that is still not qualitative. Embarrassing situation. However, open biopsy may cause local contamination, increase the difficulty of subsequent surgical resection, and affect the success rate of limb salvage. Therefore, incision biopsy is the last resort to confirm pathological diagnosis before surgery and should not be the first choice.

Regardless of the pathological tissue biopsy method, as long as the possibility of limb salvage surgery is estimated, attention must be paid to the future surgical resection area to include the puncture or biopsy path area, otherwise it may cause tumor tissue contamination in the puncture or biopsy approach The problem of recurrence.

If you have any questions, please contact us. Our company can produce various customized needles, medical needles, puncture needles, hypodermic needles, biopsy needles, vaccine needles, injection needles, syringe needles, veterinary needles, pencil point needle, ovum pick up needles, spinal needles, etc. If you need customized needle products, please contact us. We look forward to your inquiry! The quality of the products manufactured in our factory will surely satisfy you!

Please contact us if you need: zhang@sz-manners.com