What to check for childhood leukemia

Children with leukemia are checked for blood routine, bone marrow imaging, immunological typing of bone marrow cells, and leukemia-related genes.

1. Blood routine: The blood routine of children can show that both red blood cells and hemoglobin are reduced, the number of reticulocytes is mostly low, a few are normal, and nucleated red blood cells are occasionally seen in peripheral blood. reducer. Leukocyte differentiation showed blasts and immature cells in peripheral blood, and thrombocytopenia.

2. Bone marrow image: Bone marrow cytological morphological examination is the basis for establishing diagnosis and evaluating curative effect. Bone marrow showed obvious or extremely active proliferation, mainly all kinds of primitive and early immature cells, a few with low proliferation.

3. Immunological typing of bone marrow cells: The detection of bone marrow cells by flow cytometry and monoclonal antibodies is helpful for the diagnosis and identification of leukemia cell types.

4. Leukemia-related genes: Through chromosome analysis and gene detection of bone marrow cells, leukemia-related chromosomal and molecular abnormalities can be found, which is helpful for the genetic typing of leukemia, and is of great significance for guiding prognosis, typing, diagnosis and treatment.

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