What liver disease can be detected by liver biopsy

The value of liver biopsy has the following eight points:

1. It is beneficial to the differential diagnosis of various liver diseases

Many chronic liver diseases with difficult clinical diagnosis, such as various types of viral hepatitis, alcoholic hepatitis, liver tuberculosis, liver granuloma, schistosomiasis, liver tumor, fatty liver, liver abscess, primary biliary cirrhosis and various Metabolic liver diseases (hepatolenticular degeneration, hepatic glycogen storage disease, hepatic amyloidosis), etc., often require liver biopsy to understand the patient's liver lesions, which provides an important and even possibly decisive basis for a clear diagnosis.

2. Understand the extent and activity of liver lesions

Liver biopsy is an examination method that can directly understand the pathological changes of liver tissue, and can make a more objective and accurate diagnosis. There are many chronic hepatitis B patients who have been infected with liver disease virus for a long time, but it may only be half a year for abnormal transaminase detected by blood test, and the level of liver disease virus is not high. Such patients can find out whether the chronic liver disease is in the active stage through liver puncture, and can infer the severity of the disease.

3. Provide the etiological diagnosis of various types of viral hepatitis Most of the hepatitis viruses are hepatotropic viruses, and they are often parasitic in the liver tissue. Only when the serum liver disease virus reaches a certain amount, the clinical test can detect it. Therefore, there are still some viral hepatitis. Clinical tests show that serum liver disease virus markers are all negative, so it is difficult to determine the pathogen. However, by liver puncture, with ultrasensitive immunohistochemistry and in situ molecular hybridization, the hepatitis virus parasitic in liver tissue can be detected.

4. To find early, static or compensated cirrhosis. Liver cirrhosis, especially liver fibrosis, is generally difficult to detect through blood tests and B-ultrasound examinations in the early onset. However, liver biopsy can accurately diagnose liver fibrosis and liver cirrhosis in the early, static or compensated stage, and can identify the clinical types of liver cirrhosis, distinguish between alcoholic cirrhosis and post-hepatitis cirrhosis, and with active hepatitis. For example, some patients diagnosed as carriers of chronic asymptomatic liver disease may be found to be active cirrhosis or chronic active hepatitis through liver biopsy.

5. It is beneficial to the selection of drugs and the judgment of the efficacy of drugs

The pathological changes of liver biopsy before and after treatment are reliable indicators for evaluating the effect of drug treatment, and provide an objective basis for clinical drug treatment. At present, the commonly used anti-liver virus drugs are interferon and lamivudine. The application of interferon or lamivudine for antiviral treatment not only has a long course of treatment, but also is expensive. If liver puncture can be performed before treatment, according to the degree of inflammatory activity of liver tissue, selective and targeted application of antiviral drugs will significantly improve the curative effect.

6. Identify the nature and cause of jaundice

Clinically, it is often difficult to determine the cause of jaundice, and liver biopsy can be done. It can determine whether the jaundice is caused by bilirubin metabolism disorder, or hepatocellular jaundice, or caused by cholestasis, whether it is caused by a virus or a drug. Different etiologies, prognosis and treatment are completely different. Only with a clear diagnosis can a correct diagnosis and treatment plan be formulated.

7. As an evaluation index for the condition and prognosis of chronic hepatitis

Liver puncture can detect the pathological changes of liver tissue, and provide objective basis for the judgment of disease changes and prognosis. If severe hepatitis is dominated by hepatocyte edema, the disease will be milder, the prognosis will be better, and the fatality rate will be low; if the liver cell necrosis is the predominant, and the residual rate of normal hepatocytes is low, the disease will be severe, the prognosis will be poor, and the fatality rate will be low. high rate.

8. Diagnostic treatments are available

Under the guidance of B-ultrasound or CT, purposeful liver puncture can be performed to perform liver abscess puncture to drain pus, injection of drugs, and intratumoral injection of anhydrous alcohol to treat liver cancer. At the same time of puncture, sampling and diagnosis, diagnostic treatment can also be carried out, so that both diagnosis and treatment are correct.

The incidence of hemorrhage after liver puncture is about 1 in 100,000. Since liver biopsy technology is very mature, as long as the indications and contraindications are mastered, and adequate preparations are made before liver puncture, the operation of liver puncture biopsy can be performed. Foolproof.

If you have any questions, please contact us. Our company can produce various customized needles, medical needles, puncture needles, hypodermic needles, biopsy needles, vaccine needles, injection needles, syringe needles, veterinary needles, pencil point needle, ovum pick up needles, spinal needles, etc. If you need customized needle products, please contact us. We look forward to your inquiry! The quality of the products manufactured in our factory will surely satisfy you!

Please contact us if you need: zhang@sz-manners.com