What are the contraindications and indications for bone marrow aspiration

Bone marrow aspirate (1) There are few contraindications for bone marrow aspirate. Except for severe hemophilia and some coagulation factor deficiency diseases, bone marrow aspirate can be performed. Locally inflammatory or deformed puncture sites should be avoided. (2) Indications for bone marrow aspirate: ① Abnormal number and quality of peripheral blood cells, such as unexplained or (and) difficult to diagnose anemia, leukopenia, granulocytopenia, deficiency, leukemia, thrombocytopenia, hypersplenism, myeloma, Lymphoma, leukemia-like reaction and lipid-like metabolic disorders, etc. ②Unexplained liver, spleen, lymph node enlargement, fever, bone destruction, bone pain, thoracic mucus, proteinuria and kidney damage (in older age), pericardial mucus, vaginal bleeding in women, menstrual cycle disorders, penis in men Priapism and other symptoms (should be alert to leukocyte infiltration). ③ Treatment observation or other examinations are required: leukemia treatment observation, bone marrow cell immunological typing, genetic examination, and bone marrow cell culture. ④ Malignant tumors showed bone marrow metastasis, connective tissue diseases, parasitic diseases and so on.

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