The importance of genetic testing for tumor diagnosis

The concept of genetic testing is especially popular in targeted therapy. So, besides pathological diagnosis, what is the significance of genetic testing? In reality, we can observe that for patients with the same histological type, the prognosis of the patients is not different after medication. Why is this?

After the concept of genetic testing was popularized, we learned that patients of the same histological type may have different sensitivity to drugs, which directly leads to differences in treatment effects, and genetic testing can provide cancer patients with "personalized" Serve. Appropriate treatment plans and drugs make the treatment more targeted, which not only effectively avoids the adverse reactions of the patients, but also buys more treatment time for the patients and saves costs. The research results released by the American Clinical Oncology Conference showed that more than 80% of doctors changed their original treatment after tumor genetic testing.

Secondly, there is indeed a risk of tumor metastasis through the puncture tract, but almost all the time, the benefits of a needle biopsy far outweigh the risk of metastasis. According to reports, the probability of tumor metastasis caused by puncture is about 0.07%~2.33%. The reasons leading to large-scale fluctuations in probability are as follows:

The higher the degree of malignancy, the easier it is for needle tract metastasis to occur.

As the diameter of the puncture needle increases, the area in contact with the tumor increases, leading to an increase in probability.

The more punctures, the greater the probability of being hit.

After the puncture is completed, some doctors will inject ethanol into the tissue along the way where the puncture needle is withdrawn, which can make the tumor cells scattered along the way coagulate and necrotize, thereby reducing the probability of needle tract metastasis.

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