As an invasive procedure, a lumbar puncture needle may cause:

1. Injury of cauda equina nerve root: Such complications are rare in clinical practice, and are mostly related to the deviation of the puncture needle tip from the midline of the human body or accidental injury to the spinal nerve root. Symptoms such as lower extremity numbness, pain, or transient urination disturbance may occur, which often resolve spontaneously. 1. Headache: The amount of cerebrospinal fluid released is large, and the lack of supine time can lead to low intracranial pressure headache. 2. Meningeal infection: Lumbar puncture without strict disinfection can cause spinal osteomyelitis, intervertebral disc infection, epidural abscess or bacterial meningitis. 3. Brain herniation formation: For patients with high intracranial pressure and posterior cranial fovea space-occupying lesions, detailed medical history and physical examination should be inquired before lumbar puncture, and corresponding treatment to lower intracranial pressure should be done, otherwise it may lead to foramen magnum hernia. 4. Low back pain: mainly due to nerve root injury or pinhole bevel cut ligament during lumbar puncture.

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