Absolute contraindication of lung needle biopsy

1. Patients with severe bleeding tendency, platelet < 50*109/L (100-300) ×109/L and severe coagulation disorder [prothrombin time >18(12-14)s, prothrombin activity < 40% (75%-100%)]; Anticoagulant therapy and/or antiplatelet drugs should be discontinued at least 5-7 days prior to biopsy;

2. Patients with cardiac insufficiency or myocardial infarction or severe cardiac arrhythmia;

3. The lesions to be sampled were suspected vasogenic lesions (pulmonary isolation, arteriovenous malformation, aneurysm, etc.).

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