When is fine-needle aspiration of the thyroid gland necessary?

1. All thyroid nodules with a diameter of ≥ 1 cm can be considered for FNAB examination, but FNAB is not routinely used in the following cases: ① It is confirmed as a "hot nodule" with autonomous uptake function by thyroid radionuclide imaging. ② Ultrasound showed pure cystic nodules. ③ Nodules that are highly suspected to be malignant according to ultrasound images.

2. For thyroid nodules <1cm in diameter, routine FNAB is not recommended. However, FNAB can be considered if there are any of the following conditions: (1) nodules with malignant signs on ultrasound; (2) abnormal ultrasound images of cervical lymph nodes; (3) a history of cervical radiation exposure or exposure to radiation contamination in childhood; (4) thyroid cancer or thyroid cancer Medical history or family history of cancer syndrome; ⑤ 18F-FDG PET imaging was positive; ⑥ with abnormally elevated serum Ct level.

3. "Obviously growing" nodules with the adaptation sign of FNAB. "Significant growth" is defined as a nodule with an increase of more than 50% in volume or an increase of more than 20% (and more than 2 mm) in at least 2 diameters, and for cystic-solid nodules, based on the growth of the solid part. (Correspondent Guodong)

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