When is a liver biopsy required?

Liver biopsy (liver biopsy) is a very mature operation technique. Patients only need local anesthesia. Under the guidance of ultrasound or CT, a specific liver biopsy gun is used to guide the puncture of the liver through the skin, and liver tissue samples are taken for Histopathological examination. Generally speaking, liver biopsy is mainly used in three situations:

1. It is used to diagnose unknown liver diseases: abnormal liver function and hepatomegaly of unknown cause; intrahepatic space-occupying lesions are found, and the nature of the tumor cannot be determined; to determine whether there is rejection after liver transplantation.

2. Staging of known liver diseases: to determine the activity and progression of chronic hepatitis lesions and the stage of liver fibrosis; to determine the extent of donor rejection in liver transplantation; to determine liver tumor staging and tumor differentiation.

3. For the formulation of treatment plans, efficacy judgment and prognosis analysis: to determine whether the condition of patients with chronic hepatitis B has improved after antiviral drug treatment, and whether liver fibrosis has reversed; pathological examination of liver malignant tumors to determine the prognosis of patients or the risk of tumor recurrence. risk; perform molecular subtyping of liver cancer and screen for potential benefit from targeted or immunotherapy.

In the above cases, liver biopsy can be obtained by pathological examination to obtain the "gold standard" for liver disease diagnosis and treatment.

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