What's with the particle knife

Jun 22, 2022

Radiation therapy (radiotherapy) for malignant tumors as we know it is usually done by irradiating the tumor site with external radiotherapy equipment. The radiation must pass through the skin and some normal tissues and organs to reach the tumor, which may undergo unnecessary damage. With the continuous progress of medical technology, in recent years, a new type of tumor radiotherapy technology -- high-precision interstitial tumor radiation implantation therapy (referred to as "particle knife") was born. The particle knife is used to implant tiny radioactive sources into tumor tissue precisely according to the shape of the tumor. Through its continuous low energy Y rays, so that the tumor tissue suffered destructive killing method. The advantages of this method are: the local tumor is treated with close range radiation therapy, the dose of radiation therapy is low, the duration of treatment is long, the damage to the surrounding normal tissues is small, and the lethality to tumor cells is strong. Hefei Cancer Hospital, and can avoid surgical trauma, no serious toxic and side effects, reliable curative effect, for the recent clinical treatment of cancer, one of the advanced means, and become a historical revolution in effective treatment of cancer, for cancer patients to improve the quality of life, reduce pain and prolong life time brought good news. At present, the radioactive particles commonly used in medical treatment are radioactive iodine particles with a diameter of 0.8mm and a length of 4.5mm sealed by titanium alloy shell. Therefore, radioactive iodine will not be absorbed by the human body into the blood to cause radiation pollution to the environment, and it is safe for patients, family members and medical staff. The method of particle knife surgery is to determine the location and size of the tumor through CT or MRI and calculate the number of radioactive particles used. Under the guidance of B ultrasound or CT, the particle implantation needle was percutaneous punctured into the tumor, and the radioactive particles were placed in the fully enclosed radiation implanter, and the particles were delivered into the tumor through the implantation needle. Intratumor implantation can also be performed through various endoscopes, or puncture implantation can be performed under direct vision for partially resected or unresectable tumors during surgery, and preventive implantation is more convenient at the site where tumors may spread.

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