What is the significance of pleural effusion and why does lung cancer produce pleural effusion?

Nov 09, 2022

Also known as pleural effusion, it is a very common disease, causing pleural effusion can be up to hundreds of causes, including respiratory diseases, but also involving systemic diseases such as cirrhosis, kidney disease, cardiac insufficiency, immune system diseases, parasitic infections and so on. Common respiratory etiology mainly includes: pleural metastasis of malignant tumor, tuberculous pleurisy, bacterial infection of pleural cavity. Lung cancer and tuberculous pleurisy are the two most common diseases. When pleural metastasis of lung cancer appears pleural effusion, it is already in the advanced stage and the prognosis of the disease is not good. It is of great clinical significance to identify the nature of pleural effusion. How to distinguish the benign and malignant pleural effusion, mainly rely on the test after extraction of pleural effusion, can do pleural biopsy when conditions. The good and bad of pleural effusion can be distinguished by its color, transparency, protein content, count and classification of pleural effusion cells, detection of tumor markers, growth rate of pleural effusion, response to treatment and other properties and characteristics. Therefore, the examination of pleural effusion is an essential method for the diagnosis and treatment of pleural effusion. Malignant pleural effusion is a common complication of lung cancer patients, and 50% of lung cancer patients will have pleural effusion during the course of the disease. It often causes dyspnea, chest pain cough and other symptoms, and can appear respiratory and circulatory dysfunction in severe cases. The immediate possible causes of pleural effusion in lung cancer include: 1. The increase of vascular permeability due to tumor pleural metastasis, and the amount of protein penetrating into the chest exceeds the amount of back absorption; 2. 2. Tumor compression or obstruction of lymphatic vessels and obstruction of lymphatic fluid reflux or obstruction of thoracic duct are the main mechanisms for the generation of cancerous pleural effusion; 3. Bronchial compression, resulting in reduced lung volume and reduced intrathoracic pressure; 4. Pericardial tamponade increases the hydrostatic pressure of blood vessels, resulting in fluid leakage. The indirect causes may be: 1. Hypoproteinemia; 2. Obstructive pneumonia; 2. 3. Endocrine disorders.

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