What is bone marrow puncture biopsy needle to check

Jan 08, 2023

Bone marrow aspiration biopsy is to insert a puncture needle into the bone marrow cavity for pathological examination of bone marrow tissue, which is of great significance for the diagnosis of myelodysplastic syndrome, primary or secondary myelofibrosis, hypoplastic leukemia syndrome, aplastic anemia, multiple myeloma, etc.
Bone marrow aspiration biopsy can examine bone marrow cell composition, primitive cell distribution, cell morphology, etc., and understand the overall picture of bone marrow, hematopoietic degree, myelodysplasia, and changes in bone marrow structure. For example, patients with aplastic anemia may have hypomyelodysplasia and reduced hematopoietic tissue. There are fewer nuclear cells, more fat cells and more non-hematopoietic tissue in the hematopoietic island. And patients with myelofibrosis often show positive reticular fiber staining. At this time, the degree of myelofibrosis can be clearly defined. A large number of reticular fibers and collagen fibers can be seen, and bone hyperplasia can be seen in severe cases. Bone marrow puncture biopsy can reflect the bone marrow status comprehensively, which is beneficial to the diagnosis of the above diseases.
Bone marrow aspiration biopsy is an invasive operation. After sampling, local hemostasis should be pressed to protect the wound and avoid contact with raw water to prevent infection. In addition, patients with bleeding tendencies, women in late pregnancy and children who can not cooperate should not perform the operation.

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