What is a pathological biopsy

Pathological biopsy, referred to as "biopsy", is an important method for disease diagnosis by morphological examination of living tissue. Biopsy is mainly used for the differentiation between tumor and non-tumor diseases, benign and malignant tumors, to judge the extent and scope of malignant tumor growth, invasion and metastasis, and to observe the degree of disease development or treatment response. According to the different instruments and methods used in biopsy, there are cut biopsy, which is to cut part of the lesion and its adjacent normal tissue; Excision biopsy is the removal of all lesions for examination; Endoscopic biopsy, in which a small amount of diseased tissue is taken by endoscopic forceps; Needle aspiration is a small amount of tissue sucked up with a puncture needle. In addition, there are scraping, drilling and other ways. Biopsy tissues were then selected for paraffin sections and histologically examined under a microscope, with electron microscopy or immunohistochemistry if necessary. In addition, there is a rapid biopsy, also known as a frozen biopsy, which is often used to make timely judgments during surgery to help determine the scope or method of surgery, etc.