What are the dangers of donating bone marrow to the donor?

What a noble act to dedicate one's own marrow to patients to save those dying brothers and sisters! With the development of bone marrow transplantation, more and more people responded to the work of donating bone marrow. But there are also many people who do not understand the process of donating marrow and lack the knowledge in this area, and they can't help but worry that donating marrow will affect their health. In fact, this worry is unnecessary. Many different types of blood cells in our body are derived from the same ancestor—pluripotent hematopoietic stem cells. Not only can he keep differentiating offspring, but he can also reproduce cells that are identical to himself. As a result, our hematopoietic function is inexhaustible. When old blood cells die, new ones grow to replace them; when some hematopoietic stem cells are damaged, healthy stem cells are quickly born to compensate. Our bodies work so well together. Pluripotent stem cells are not very numerous and are distributed throughout the bone marrow. When donating bone marrow, only a small part of the bone marrow is extracted from the human body, and only a part of the pluripotent stem cells are lost. The remaining pluripotent stem cells will quickly replicate, and the hematopoietic function will return to normal in a short period of time. Therefore, donating bone marrow will not affect human hematopoietic function. Some people are also afraid of the operation of donating bone marrow. Let’s introduce the operation of collecting bone marrow: after the bone marrow donor is considered qualified after a comprehensive physical examination, it is performed under continuous epidural anesthesia or general anesthesia (the anesthesia method is the same as that of general surgery), and the bone marrow is collected. Most of the parts use the ilium, commonly known as the big crotch, but also use the sternum. The method of bone marrow collection is similar to that of usual bone marrow aspiration. A few milliliters of bone marrow fluid were drawn by puncturing a needle. The amount of bone marrow harvested depends on the patient's weight and the number of cells in the donor's bone marrow fluid. The number of bone marrow cells infused should not be less than 3.0 × 108 kg of the patient's body weight. Therefore, adults generally need to donate about 800-1000 ml of bone marrow. In fact, so many bone marrow fluids are mixed with a lot of blood, so appropriate blood transfusions are required during the operation. When the required number of cells is reached, the surgery is over. After the operation, the pain in the operation area will be felt due to the large number of puncture points, which usually disappears within two weeks. Many donors can return to work 3-4 days after surgery, and the youngest donor is nearly 2.5 months old. These all show that donating bone marrow is safe for healthy people.

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