What are the contraindications and indications of bone marrow puncture needle

Bone marrow aspiration (1) Bone marrow aspiration has few contraindications, except for severe hemophilia and some coagulation factor deficiency diseases. Puncture sites with local inflammation or malformation should be avoided. (2) Indications for bone marrow biopsy: ① Patients with abnormal quantity and quality of peripheral blood cells, such as anemia, leukopenia, granulocytopenia, deficiency, leukemia, thrombocytopenia, hypersplenism, myeloma, lymphoma, leukemia-like reaction and lipid metabolism disorders, are of unknown cause or (and) difficult to diagnose. ② Unexplained liver, spleen, lymphadenopathy, fever, bone destruction, bone pain, chest mucus, proteinuria and kidney damage (older), pericardial mucus, female vaginal bleeding, menstrual cycle disorders, male priapism and other symptoms (should be vigilant against leukocyte invasion). ③ Treatment observation or other examination: leukemia treatment observation, bone marrow cell immunotyping, genetic examination and bone marrow cell culture, etc. ④ Malignant tumors presented bone marrow metastasis, connective tissue disease, parasitic disease, etc.

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