Under what circumstances should liver puncture not be performed?

Apr 15, 2022

Puncture is short for liver biopsy. Patients usually need local anesthesia, use the negative pressure suction one-second puncture technique, percutaneous puncture under the positioning and guidance of B-ultrasound and CT, or direct puncture under the monitoring of laparoscopy. The liver samples obtained by puncture are generally about 10-25 mg. After processing, they are stained for histopathology and immunohistochemistry. The liver tissue and cell morphology are observed under a microscope.

Liver puncture is mainly used for the differential diagnosis of various liver diseases, such as identifying the nature and causes of jaundice, understanding the degree and activity of liver lesions, providing the basis for the etiological diagnosis of various types of viral hepatitis, and finding early, stationary or It is an internationally recognized gold standard for judging clinical efficacy, especially in determining the severity of liver fibrosis, in patients with liver cirrhosis in the compensated stage. In addition, liver puncture can also be used for diagnostic treatment, such as liver abscess puncture to drain pus, liver cyst fluid extraction, intratumoral injection of drugs or anhydrous alcohol, etc.

Severe jaundice, massive ascites and coagulation disorders, congestive hepatomegaly, acute inflammation of the right thoracic cavity and subdiaphragm, suspected hepatic hydatid disease or hepatic hemangioma are contraindications for liver biopsy.

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