Is liver biopsy necessary after liver transplantation?

After liver transplantation, the liver is generally a preferential organ for immunity. Therefore, liver transplant patients take relatively small amounts of immunosuppressants, and the probability of acute rejection is also relatively low. Therefore, when a patient has acute rejection, needle biopsy is often needed to confirm, because pathological diagnosis is the gold standard for acute rejection of liver transplant patients. Liver needle biopsy is used to determine whether there is rejection in the transplanted liver. Treatment, as a definite basis for diagnosis, is now better due to the development of immunosuppressive drugs.

In addition, liver transplantation clinicians have rich experience, and not all patients with acute rejection need to be diagnosed with liver biopsy. Often through clinical judgment, the patient's signs include imaging B-ultrasound, some biochemical indicators detection. When we judge the clinical diagnosis of liver rejection, we can start the treatment. The puncture is not a liver transplant, but a routine treatment, only for some special diseases. When we cannot distinguish the transplanted liver because of acute rejection, drug-induced liver damage, or viral infection, or the recurrence of the primary disease, we only use needle biopsy to assist in the diagnosis.

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