Is it painful to be a test tube baby?

To understand whether IVF is painful or not, the best entry point is to look at its process.

Ovulation induction treatment

On day 2 of the menstrual cycle, or after satisfactory suppression of the GnRH agonist (reproductive hormones and utero-ovarian ultrasonography results), women start ovulation induction drugs. The doctor judges the follicle growth according to the results of ultrasound monitoring and serum hormone determination, and decides whether to adjust the dosage of ovulation induction drugs. When the follicles mature, hCG injections are given to promote the final maturation of the eggs. Eggs are usually retrieved 36-38 hours after the hCG injection.

egg retrieval

Under the guidance of B-ultrasound, the doctor uses a special egg retrieval needle to puncture the mature follicle through the vagina and aspirate the egg. Egg retrieval is usually performed under intravenous anesthesia, so the woman does not feel the pain of the puncture procedure.

In vitro fertilization

Sperm retrieval: While the female retrieves the eggs, the male retrieves the sperm. After the semen goes through a special washing process, the sperm and eggs are placed in a special medium in order to combine naturally. This is called conventional fertilization.

Embryo Transfer

A few days after fertilization, a very thin embryo transfer tube is used to transfer the best embryos into the mother’s uterus through the cervix. The number of embryos to transfer is determined according to age, embryo quality and previous IVF outcomes, usually 2-3 embryo. In recent years, in order to reduce the multiple pregnancy rate, some centers choose single embryo transfer, or transfer up to 2 embryos.

Because the embryo transfer tube is thin and the doctor moves gently, the patient usually does not experience any pain.

luteal support

Women often have luteal insufficiency during the oocyte retrieval cycle due to the use of GnRH agonists/antagonists and ovulation-inducing drugs, as well as the loss of granulosa cells from oocyte retrieval, requiring progesterone and/or chorionic gonadotropin for luteal insufficiency Supplement/support. If not pregnant, stop progesterone and wait for menstruation. If pregnant, continue to use progesterone, usually until 3 weeks after the fetal heart rate is seen on ultrasound.

determination of pregnancy

Serum HCG was determined 14 days after embryo transfer to determine pregnancy. Serum HCG was measured again 21 days after embryo transfer to understand the status of embryo development. Transvaginal ultrasonography was performed 30 days after embryo transfer to determine whether there was an intrauterine pregnancy and the presence or absence of fetal heartbeat.

To sum up, in general, being a test-tube baby will not bring a lot of pain to women. But everyone's physical condition is different, and everything will be fine if you follow the doctor's advice.

Through the introduction of this article, we can know that being a test-tube baby will still make women suffer some hardships. But in order to have a healthy and smart baby, many women can live with the pain. If you want to be a test tube baby, then you have to be mentally prepared to suffer a little.

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