Is bone marrow puncture dangerous?

Jun 15, 2022

Diseases with abnormal hematopoietic cells or tissues, blood cells, and hemostatic system are called hematologic diseases. Blood cells, including red blood cells, white blood cells and platelets, are derived from hematopoietic cells and tissues. In adults, hematopoietic cells and tissues are mainly found in bone marrow. In some special cases, the liver and spleen also participate in hematopoiesis. Bone marrow examination is one of the most important examination methods for blood diseases. Because hematopoietic cells are mainly found in the bone marrow, blood tests for many blood diseases (especially in the early stages) do not reflect the condition of the disease. The diagnosis, treatment effect and prognosis of many blood diseases should be determined by examining bone marrow cells. Bone marrow cells or tissues can be extracted for morphological analysis, blood cell chemical staining, chromosomal karyotype examination, immunological examination, gene analysis, stem cell culture, electron microscope examination, pathological tissue examination, etc. Bone puncture or biopsy is necessary to obtain bone marrow cells or tissues. Bone marrow cell morphology examination is the most valuable examination method for the diagnosis of hematopoietic system diseases, such as leukemia, multiple myeloma, aplastic anemia, megaloblastic anemia, etc. To observe the curative effect and prognosis of the disease; Bone marrow examination is also used to diagnose non-hematopoietic diseases, such as parasitic infections (malaria, kala-azar), metabolic diseases (Gaucher's disease, Niemann-pick disease), metastatic bone marrow cancer; Bone marrow examination can be made for fever of unknown cause, cachexia, enlargement of liver, spleen and lymph node of unknown cause, bone pain, single or multiple unexplained decrease and increase of naive cells, suspicious cells and blood cells in peripheral blood; Biopsy and multiple bone marrow examinations are sometimes required. The pathological changes of bone marrow in some diseases are focal changes, and a bone marrow puncture can only reflect the bone marrow function or pathological status at the puncture site. Does not reflect the overall condition of the bone marrow. In addition to bone marrow cytology, the diagnosis of some diseases still needs to know the changes of bone marrow tissue structure. In addition, bone marrow dry aspiration and other conditions should be combined with bone marrow biopsy for pathological examination. Pathological examination was performed in conjunction with bone marrow biopsy. Bone marrow biopsy or biopsy is a very simple and safe operation, namely before raised such as iliac bone in the spine, after iliac spine, the place such as s, after the local anesthetic first with bone marrow puncture needle or a biopsy needle into the extract some take a small piece of tissue to check blood or bone marrow, will soon be able to complete, such as patients do not need hospital treatment, can go home immediately after piercing. There are many bones all over the body that can produce blood. Taking a small amount of bone marrow blood or a small piece of bone marrow tissue is insignificant and has no effect on the body. There was no complication in the process of bone puncture in our hospital. If the patient has a history or family history of persistent bleeding, or a history of drug allergies, tell your doctor before the puncture. There were concerns that bone piercing could injure the body or even endanger life; Some people think of the bone marrow and spinal cord as the same organ, so the idea of a bone marrow puncture as a spinal tap is wrong.

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