I wonder if I could donate bone marrow twice

Many of the types of blood cells in our bodies come from the same ancestor, the pluripotent hematopoietic stem cell. Not only does he keep producing offspring, but he can make copies of his own cells. Which keeps our blood production going. When old blood cells die, new ones grow to replace them; When some blood-forming stem cells are damaged, healthy stem cells are quickly born to compensate. Our bodies work so well together. Pluripotent stem cells are not very numerous and are distributed throughout the bone marrow. When bone marrow is donated, only a small part of the bone marrow is extracted from the body, and only a part of the pluripotent stem cells are lost. The remaining pluripotent stem cells will quickly replicate and the hematopoietic function will completely return to normal in a short time. So bone marrow donation will not affect the hematopoietic function.

Some people are afraid of the operation of bone marrow donation. Here is an introduction to the operation of bone marrow collection: After a comprehensive physical examination, the marrow donor is considered qualified, and it is carried out under continuous epidural anesthesia or general anesthesia (the anesthesia method is the same as the general surgery). The site of bone marrow collection is mostly iliac bone, which is commonly known as the greater hipbone, and also sternum. The method of medullary extraction is similar to that of bone marrow aspiration. Take a few milliliters of marrow fluid from a needle. The amount of bone marrow extracted depends on the patient's body weight and the number of cells in the donor's bone marrow fluid. The number of bone marrow cells input should not be less than 3.0×108 kg of patient weight, too little is not easy to transplant successfully. So the average adult needs to donate about 800-1000 milliliters of bone marrow. In fact, so much bone marrow fluid mixed with a lot of blood, so the operation must be appropriate transfusion. When the number of cells is sufficient, the operation is over. Postoperative pain in the surgical area will be felt due to the large number of puncture points, which will gradually disappear within two weeks. Many marrow donors return to work within 3 to 4 days after surgery, with the smallest being nearly 2.5 months. All these indicate that bone marrow donation is safe for healthy people.