A sudden increase in creatinine can be seen for many reasons

For example, renal vascular diseases, such as renal artery thrombosis, atherosclerotic plaque, aortic dissection, and renal vein thrombosis, can also cause a sudden increase in creatinine;

In addition, due to some inflammations of the glomeruli and kidneys, such as acute or rapidly progressive glomerulonephritis, acute exacerbations of chronic glomerulonephritis, lupus nephritis and some hemolytic uremic syndromes;

Some malignant hypertension, hypercalcemia, and pre-eclampsia can also cause a sudden increase in creatinine;

In addition, we can also see some allergic interstitial nephritis, such as caused by drugs, food or toxic substances;

In addition, bacterial, viral, and fungal infections can also cause a sudden increase in creatinine;

In addition, some patients are due to tumor infiltration, such as lymphoma and leukemia, which can also cause a sudden increase in creatinine, so a sudden increase in creatinine can be seen for many reasons.

Creatinine is a metabolic waste of the human body, which is mainly excreted by the kidneys. Therefore, when creatinine rises, it indicates renal dysfunction. For a sudden increase in creatinine, this condition is acute renal insufficiency, so further clarification of the cause is needed. It is common clinically due to renal ischemia, rapidly progressive glomerulonephritis, acute interstitial nephritis, acute tubular necrosis and other reasons.

When necessary, renal biopsy can be checked to further clarify the pathological damage, and targeted medication treatment. For this type of acute kidney injury, after active symptomatic treatment and treatment to remove the cause, it is possible for renal function to return to normal. Also pay attention to regular follow-up visits to the hospital to monitor changes in the condition.

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