Why Is Myelofibrosis [bone Marrow Aspirate] Difficult?
May 10, 2018
Why does the proliferation of fibroblasts lead to changes in the composition of the bone marrow and become dominated by fibroblasts instead of hematopoietic cells. These fibroblasts are relatively stiffer than those of blood cells. The hardness of the entire bone marrow will increase. When doctors use the commonly used puncture needle for bone marrow puncture, they will naturally encounter difficulties, resulting in difficulty in puncturing.
This disease will also cause the human bone marrow to not be able to make sufficient hematopoiesis, so other parts other than the bone marrow are required to make hematopoiesis, otherwise people will have problems. Therefore, the most common hematopoietic part, the spleen, bears the brunt of the hematopoietic organ, and its hematopoiesis increases the The workload, therefore, the spleen will be enlarged.
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