What Liver Piercing Needle Can Detect Liver Disease To Come

The value of liver biopsy has the following eight points:

1. It is beneficial to the differential diagnosis of various liver diseases

Many chronic liver diseases with difficult clinical diagnosis, such as viral hepatitis, alcoholic hepatitis, liver tuberculosis, liver granuloma, schistosomiasis, liver tumor, fatty liver, liver abscess, primary biliary cirrhosis and various metabolic liver diseases (Wilson's disease, liver glycogen accumulation disease, liver amyloidosis), often need to understand the patient's liver disease through liver aspiration. Provide important and possibly decisive evidence for a definitive diagnosis.

2. Understand the extent and activity of liver lesions

Liver biopsy is a kind of examination method that can directly understand the pathological changes of liver tissue and make objective and accurate diagnosis. Many patients with chronic hepatitis B have been infected with liver disease virus for a long time, but the abnormal transaminase found in blood tests may only be half a year, and the content level of liver disease virus is not high. Such patients can find out whether the chronic liver disease is in the active stage through liver puncture, and can infer the severity of the disease.

3. Provide the basis for etiological diagnosis of various types of viral hepatitis. Most hepatitis viruses are hephotropic viruses, which tend to parasitise liver tissue. Only when the serum liver disease virus reaches a certain level, clinical tests can be detected. Therefore, there are still some viral hepatitis, and clinical tests show that the serum viral markers of liver disease are all negative, so it is difficult to determine the etiology. However, the hepatitis virus in liver tissue can be detected by liver puncture, ultra sensitive immunohistochemistry and in situ molecular hybridization.

4. Early, still or compensatory cirrhosis Cirrhosis, especially liver fibrosis, in the early stage of the disease, by blood tests, B-ultrasound examination is generally difficult to detect. However, liver biopsy allows accurate diagnosis of fibrosis and early, inactive, or compensatory cirrhosis, and can differentiate the clinical type of cirrhosis from alcoholic cirrhosis, posthepatitis cirrhosis, and whether it is accompanied by active hepatitis. For example, some patients diagnosed as chronic asymptomatic liver disease virus carriers may be found to have active cirrhosis or chronic active hepatitis by liver biopsy.

5. It is beneficial to the selection of drugs and the judgment of the efficacy of drugs

The pathological change of liver biopsy tissue before and after treatment is a reliable index to evaluate the efficacy of drug therapy, and provides an objective evaluation basis for clinical drug therapy. At present, the commonly used drugs against liver disease virus are interferon and lamivudine. The application of interferon or lamivudine for antiviral treatment is not only a long course of treatment, but also expensive. If liver puncture can be performed before treatment, selective and targeted application of antiviral drugs according to the degree of inflammatory activity of liver tissue will significantly improve the efficacy.

6. Identify the nature and cause of jaundice

Clinical jaundice is often difficult to determine the cause of liver biopsy can be done. It can determine whether jaundice is caused by bilirubin metabolism disorder, or hepatocellular jaundice, or cholestasis, viral or drug. Different etiology, prognosis and treatment are completely different, only clear diagnosis, in order to develop the correct diagnosis and treatment plan.

7. As an indicator of chronic hepatitis condition and prognosis

Hepatocentesis can detect the lesions of liver tissue and provide objective basis for the prognosis. If severe hepatitis is mainly hepatocyte edema, the disease is mild, the prognosis is good, and the mortality is low. If the liver cell necrosis is dominant and the normal liver cell survival rate is low, the disease is serious, the prognosis is poor, and the mortality is high.

8. Diagnostic treatment is available

Under the guidance of B ultrasound or CT, liver puncture with purpose can carry out liver abscess puncture and discharge, drug injection, anhydrous alcohol intratumal injection to treat liver cancer, etc. At the same time of puncture sampling and diagnosis, diagnostic treatment can also be carried out, so that diagnosis and treatment are not wrong.

The incidence of bleeding after liver puncture is about one in 100,000. Since the liver biopsy technology is very mature, the operation of liver biopsy can be foolproof as long as the indications and contraindications are well mastered and adequate preparation is made before liver puncture.